Magnol-RX combines a high-potency honokiol/magnolol extract from Magnolia officinalis bark (100 mg per capsule) with standardized Rhodiola rosea root extract (3% rosavin, 1% salidroside; 400 mg per capsule) to target vital exhaustion, burnout, HPA-axis dysregulation, and neuroendocrine stress failure. The formula addresses Qi depletion and Shen disturbance in TCM terms, and in biomedical terms acts through GABAA receptor potentiation, adaptogenic HPA-axis normalisation, mitochondrial energy restoration, inflammatory cytokine down-regulation, and autonomic rebalance. It is designed to produce genuine recovery of adaptive capacity (allostatic load clearing) rather than stimulant-type masking or sedative suppression.